Publications

2017

Injury-stimulated Sonic hedgehog expression in microglia contributes to neuroinflammatory response in the MPTP model of Parkinson's disease

Jeong Hwi Lee, Young Cheul Chung, Eugene Bok, Hankyu Lee, Sue Hee Huh, Ji Eun Lee, Byung Kwan Jin, Hyuk Wan Ko

https://pubmed.ncbi.nlm.nih.gov/27899315/

2017

Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors.

Deepak Bhattarai, Joo Hyun Jung, Seunghyeon Han, Hankyu Lee, Soo Jin Oh, Hyuk Wan Ko, Kyeong Lee

https://pubmed.ncbi.nlm.nih.gov/27810591/

2016

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signaling and causes short rib-polydactyly syndrome.

S Paige Taylor, Michaela Kunova Bosakova, Miroslav Varecha, Lukas Balek, Tomas Barta, Lukas Trantirek, Iva Jelinkova, Ivan Duran, Iva Vesela, Kimberly N Forlenza, Jorge H Martin, Ales Hampl, Michael Bamshad, Deborah Nickerson, Margie L Jaworski, Jieun Song, Hyuk Wan Ko, Daniel H Cohn, Deborah Krakow, Pavel Krejci

https://pubmed.ncbi.nlm.nih.gov/27466187/

2016

Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.

Hankyu Lee, Hyuk Wan Ko

https://pubmed.ncbi.nlm.nih.gov/27793670/